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Dr. A. Y. Joe

Dr. A. Y. Joe

Facharzt Nuklearmedizin

Lebenslauf Dr. Alexius Y. Joe

Jahrgang 1972

Studium

06/1991 – 12/1991 Studium Koreanisch als Fremdsprache an der Seoul National University, Süd-Korea

1992 – 1999 Studium der Humanmedizin, Albert-Ludwigs-Universität, Freiburg

 

Berufliche Tätigkeit

01/2000 – 06/2001 Arzt im Praktikum in der Radiologischen Universitätsklinik Freiburg

08/2001 – 04/2006 Wissenschaftlicher Mitarbeiter in der Klinik und Poliklinik für Nuklearmedizin des Universitätsklinikums Bonn

07/2002 – 09/2002 DAAD-Stipendium für Nachwuchswissenschaftler University Hospital der Seoul National University, Süd-Korea

seit 04/2005 Facharzt für Nuklearmedizin / Fachkunde nach StrlSchV

05/2006-03/2010 Niedergelassener Nuklearmediziner in Mönchengladbach

seit 04/2010 Niedergelassener Nuklearmediziner in Bad Honnef

 

Promotion

11/2007 Veränderungen der funktionellen Interaktion des mesiotemporlaen Kortex bei Patienten mit therapieresistenter Depression unter Vagusnervstimulation

Doktorvater: Prof. Dr. med. Hans-Jürgen Biersack

Publikationen (Pubmed Stand 2015):

1: Bosch OG, Wagner M, Jessen F, Kühn KU, Joe A, Seifritz E, Maier W, Biersack
HJ, Quednow BB. Verbal memory deficits are correlated with prefrontal
hypometabolism in (18)FDG PET of recreational MDMA users. PLoS One. 2013 Apr
9;8(4):e61234. doi: 10.1371/journal.pone.0061234. Print 2013. PubMed PMID:
23585882; PubMed Central PMCID: PMC3621736.

2: Scheef L, Spottke A, Daerr M, Joe A, Striepens N, Kölsch H, Popp J, Daamen M,
Gorris D, Heneka MT, Boecker H, Biersack HJ, Maier W, Schild HH, Wagner M, Jessen
F. Glucose metabolism, gray matter structure, and memory decline in subjective
memory impairment. Neurology. 2012 Sep 25;79(13):1332-9. Epub 2012 Aug 22. PubMed
PMID: 22914828.

3: Bucerius J, Joe AY, Herder E, Brockmann H, Biermann K, Palmedo H, Tiemann K,
Biersack HJ. Pathological 99mTc-sestamibi myocardial perfusion scintigraphy is
independently associated with emerging cardiac events in elderly patients with
known or suspected coronary artery disease. Acta Radiol. 2011 Feb 1;52(1):52-8.
doi: 10.1258/ar.2010.090482. PubMed PMID: 21498326.

4: Bucerius J, Joe AY, Herder E, Brockmann H, Reinhardt MJ, Palmedo H, Tiemann K,
Biersack HJ. Significant association of female gender with lower degree of
pathological 99mTc-sestamibi scintigraphy results as well as higher
cardiac-related deaths free survival in elderly patients. Med Klin (Munich). 2010
Dec;105(12):901-9. doi: 10.1007/s00063-010-1155-y. Epub 2011 Jan 16. PubMed PMID:
21240589.

5: Brockmann H, Zobel A, Schuhmacher A, Daamen M, Joe A, Biermann K, Schwab SG,
Biersack HJ, Maier W, Boecker H. Influence of 5-HTTLPR polymorphism on resting
state perfusion in patients with major depression. J Psychiatr Res. 2011
Apr;45(4):442-51. doi: 10.1016/j.jpsychires.2010.08.016. Epub 2010 Oct 8. PubMed
PMID: 20934189.

6: Brockmann H, Zobel A, Joe A, Biermann K, Scheef L, Schuhmacher A, von Widdern
O, Metten M, Biersack HJ, Maier W, Boecker H. The value of HMPAO SPECT in
predicting treatment response to citalopram in patients with major depression.
Psychiatry Res. 2009 Aug 30;173(2):107-12. doi:
10.1016/j.pscychresns.2008.10.006. Epub 2009 Jun 21. PubMed PMID: 19540732.

7: Bucerius J, Joe AY, Herder E, Brockmann H, Biermann K, Palmedo H, Tiemann K,
Biersack HJ. Hemodynamic variables during stress testing can predict referral to
early catheterization but failed to show a prognostic impact on emerging cardiac
events in patients aged 70 years and older undergoing exercise (99m)Tc-sestamibi
myocardial perfusion scintigraphy. Int J Cardiovasc Imaging. 2009
Aug;25(6):569-79. doi: 10.1007/s10554-009-9461-2. Epub 2009 Apr 21. PubMed PMID:
19381866.

8: Bucerius J, Naubereit A, Joe AY, Ezziddin S, Biermann K, Risse J, Palmedo H,
Oldenburg J, Biersack HJ. Subclinical hyperthyroidism seems not to have a
significant impact on systemic anticoagulation in patients with coumarin therapy.
Thromb Haemost. 2008 Nov;100(5):803-9. PubMed PMID: 18989524.

9: Wüllner U, Gündisch D, Herzog H, Minnerop M, Joe A, Warnecke M, Jessen F,
Schütz C, Reinhardt M, Eschner W, Klockgether T, Schmaljohann J. Smoking
upregulates alpha4beta2* nicotinic acetylcholine receptors in the human brain.
Neurosci Lett. 2008 Jan 3;430(1):34-7. Epub 2007 Oct 22. PubMed PMID: 17997038.

10: Bucerius J, Wallny T, Brackmann HH, Joe AY, Roedel R, Biersack HJ, Palmedo H.
Rhenium-186 hydroxyethylidenediphosphonate (186Re HEDP) for the treatment of
hemophilic arthropathy: first results. Clin J Pain. 2007 Sep;23(7):612-8. PubMed
PMID: 17710012.

11: Bucerius J, Joe AY, Lindstaedt I, Manka-Waluch A, Reichmann K, Ezziddin S,
Palmedo H, Biersack HJ. Single- vs. dual-head SPECT for detection of myocardial
ischemia and viability in a large study population. Clin Imaging. 2007
Jul-Aug;31(4):228-33. PubMed PMID: 17599615.

12: Schlaepfer TE, Cohen MX, Frick C, Kosel M, Brodesser D, Axmacher N, Joe AY,
Kreft M, Lenartz D, Sturm V. Deep brain stimulation to reward circuitry
alleviates anhedonia in refractory major depression. Neuropsychopharmacology.
2008 Jan;33(2):368-77. Epub 2007 Apr 11. PubMed PMID: 17429407.

13: Manka-Waluch A, Palmedo H, Reinhardt MJ, Joe AY, Manka C, Guhlke S, Biersack
HJ, Bucerius J. Myocardial uptake characteristics of three 99mTc-labeled tracers
for myocardial perfusion imaging one hour after rest injection. Ann Nucl Med.
2006 Dec;20(10):663-70. PubMed PMID: 17385304.

14: Bucerius J, Ahmadzadehfar H, Hortling N, Joe AY, Palmedo H, Biersack HJ.
Incidental diagnosis of a PSA-negative prostate cancer by 18FDG PET/CT in a
patient with hypopharyngeal cancer. Prostate Cancer Prostatic Dis.
2007;10(3):307-10. Epub 2007 Mar 13. PubMed PMID: 17353915.

15: Joe AY, Tielmann T, Bucerius J, Reinhardt MJ, Palmedo H, Maier W, Biersack
HJ, Zobel A. Response-dependent differences in regional cerebral blood flow
changes with citalopram in treatment of major depression. J Nucl Med. 2006
Aug;47(8):1319-25. PubMed PMID: 16883012.

16: Bucerius J, Herkel C, Joe AY, Altehoefer C, Finke J, Moser E, Reinhardt MJ.
(18)F-FDG PET and conventional imaging for assessment of Hodgkin’s disease and
non Hodgkin’s lymphoma. An analysis of 193 patient studies. Nuklearmedizin.
2006;45(3):105-10; quiz N25-6. English, German. PubMed PMID: 16710505.

17: Bucerius J, Joe AY, Palmedo H, Reinhardt MJ, Biersack HJ. Impact of
short-term hypothyroidism on systemic anticoagulation in patients with thyroid
cancer and coumarin therapy. Thyroid. 2006 Apr;16(4):369-74. PubMed PMID:
16646683.

18: Schmaljohann J, Gündisch D, Minnerop M, Bucerius J, Joe A, Reinhardt M,
Guhlke S, Biersack HJ, Wüllner U. In vitro evaluation of nicotinic acetylcholine
receptors with 2-[18F]F-A85380 in Parkinson’s disease. Nucl Med Biol. 2006
Apr;33(3):305-9. Epub 2006 Mar 9. PubMed PMID: 16631078.

19: Bucerius J, Joe AY, Schmaljohann J, Gündisch D, Minnerop M, Biersack HJ,
Wüllner U, Reinhardt MJ. Feasibility of 2-deoxy-2-[18F]fluoro-D-glucose-
A85380-PET for imaging of human cardiac nicotinic acetylcholine receptors in
vivo. Clin Res Cardiol. 2006 Feb;95(2):105-9. Epub 2006 Jan 19. Erratum in: Clin
Res Cardiol. 2006 Jun;95(6):354. PubMed PMID: 16598519.

20: Palmedo H, Bucerius J, Joe A, Strunk H, Hortling N, Meyka S, Roedel R, Wolff
M, Wardelmann E, Biersack HJ, Jaeger U. Integrated PET/CT in differentiated
thyroid cancer: diagnostic accuracy and impact on patient management. J Nucl Med.
2006 Apr;47(4):616-24. PubMed PMID: 16595495.

21: Reinhardt MJ, Biermann K, Wissmeyer M, Juengling FD, Brockmann H, von Mallek
D, Ezziddin S, Joe AY, Krause TM. Dose selection for radioiodine therapy of
borderline hyperthyroid patients according to thyroid uptake of
99mTc-pertechnetate: applicability to unifocal thyroid autonomy? Eur J Nucl Med
Mol Imaging. 2006 May;33(5):608-12. Epub 2006 Mar 16. PubMed PMID: 16541268.

22: Reinhardt MJ, Joe AY, Jaeger U, Huber A, Matthies A, Bucerius J, Roedel R,
Strunk H, Bieber T, Biersack HJ, Tüting T. Diagnostic performance of whole body
dual modality 18F-FDG PET/CT imaging for N- and M-staging of malignant melanoma:
experience with 250 consecutive patients. J Clin Oncol. 2006 Mar 1;24(7):1178-87.
PubMed PMID: 16505438.

23: Brockmann H, Joe A, Palmedo H, Biersack HJ. A patient with acromegaly
presenting with polyostotic fibrous dysplasia on bone scan: McCune-Albright
syndrome. Clin Nucl Med. 2005 Dec;30(12):813-5. PubMed PMID: 16319643.

24: Palmedo H, Urbach H, Bender H, Schlegel U, Schmidt-Wolf IG, Matthies A,
Linnebank M, Joe A, Bucerius J, Biersack HJ, Pels H. FDG-PET in immunocompetent
patients with primary central nervous system lymphoma: correlation with MRI and
clinical follow-up. Eur J Nucl Med Mol Imaging. 2006 Feb;33(2):164-8. Epub 2005
Oct 12. PubMed PMID: 16220304.

25: Reinhardt MJ, Wiethoelter N, Matthies A, Joe AY, Strunk H, Jaeger U, Biersack
HJ. PET recognition of pulmonary metastases on PET/CT imaging: impact of
attenuation-corrected and non-attenuation-corrected PET images. Eur J Nucl Med
Mol Imaging. 2006 Feb;33(2):134-9. Epub 2005 Sep 29. PubMed PMID: 16193313.

26: Minnerop M, Joe A, Lutz M, Bauer P, Urbach H, Helmstaedter C, Reinhardt M,
Klockgether T, Wüllner U. Putamen dopamine transporter and glucose metabolism are
reduced in SCA17. Ann Neurol. 2005 Sep;58(3):490-1. PubMed PMID: 16130104.

27: Strunk H, Bucerius J, Jaeger U, Joe A, Flacke S, Reinhardt M, Hortling N,
Palmedo H. [Combined FDG PET/CT imaging for restaging of colorectal cancer
patients: impact of image fusion on staging accuracy]. Rofo. 2005
Sep;177(9):1235-41. German. PubMed PMID: 16123869.

28: Zobel A, Joe A, Freymann N, Clusmann H, Schramm J, Reinhardt M, Biersack HJ,
Maier W, Broich K. Changes in regional cerebral blood flow by therapeutic vagus
nerve stimulation in depression: an exploratory approach. Psychiatry Res. 2005
Aug 30;139(3):165-79. PubMed PMID: 16043331.

29: Brockmann H, Wilhelm K, Joe A, Palmedo H, Biersack HJ. Nasolacrimal drainage
obstruction after radioiodine therapy: case report and a review of the
literature. Clin Nucl Med. 2005 Aug;30(8):543-5. Review. PubMed PMID: 16024949.

30: Schmaljohann J, Gündisch D, Minnerop M, Joe A, Bucerius J, Dittmar C, Jessen
F, Guhlke S, Wüllner U. A simple and fast method for the preparation of n.c.a.
2-[18F]F-A85380 for human use. Appl Radiat Isot. 2005 Oct;63(4):433-5. PubMed
PMID: 16024252.

31: Kinkel B, Palmedo H, Joe A, Albert G, Biersack HJ. [Unspecific abdominal
complaints: diagnosis with szintigraphy]. Internist (Berl). 2005
Mar;46(3):329-33. German. PubMed PMID: 15750844.

32: Minnerop M, Kornblum C, Joe AY, Tatsch K, Kunz WS, Klockgether T, Wüllner U,
Reinhardt MJ. Dopamine transporter SPECT in patients with mitochondrial
disorders. J Neurol Neurosurg Psychiatry. 2005 Jan;76(1):118-20. PubMed PMID:
15608010; PubMed Central PMCID: PMC1739307.

33: Kühn KU, Joe AY, Meyer K, Reichmann K, Maier W, Rao ML, Reinhardt MJ,
Biersack HJ, Quednow BB. Neuroimaging and 5-HT2C receptor polymorphism: a
HMPAO-SPECT study in healthy male probands using mCPP-challenge of the 5-HT2C
receptor. Pharmacopsychiatry. 2004 Nov;37(6):286-91. PubMed PMID: 15551195.

34: Palmedo H, Manka-Waluch A, Albers P, Schmidt-Wolf IG, Reinhardt M, Ezziddin
S, Joe A, Roedel R, Fimmers R, Knapp FF Jr, Guhlke S, Biersack HJ. Repeated
bone-targeted therapy for hormone-refractory prostate carcinoma: tandomized phase
II trial with the new, high-energy radiopharmaceutical rhenium-188
hydroxyethylidenediphosphonate. J Clin Oncol. 2003 Aug 1;21(15):2869-75. PubMed
PMID: 12885803.

35: von Mallek D, Joe A, Palmedo H, Matthies A, Biersack HJ, Reinhardt MJ.
Improved diagnosis of advanced bone marrow metastases by means of radiolabeled
antigranulocyte antibodies. J Exp Clin Cancer Res. 2002 Sep;21(3):421-4. PubMed
PMID: 12385588.

36: Reinhardt MJ, Brink I, Joe AY, Von Mallek D, Ezziddin S, Palmedo H, Krause
TM. Radioiodine therapy in Graves‘ disease based on tissue-absorbed dose
calculations: effect of pre-treatment thyroid volume on clinical outcome. Eur J
Nucl Med Mol Imaging. 2002 Sep;29(9):1118-24. Epub 2002 Jun 26. PubMed PMID:
12192554.

37: v Maydell B, Kopp M, v Komorowski G, Joe A, Juengling FD, Korinthenberg R.
Hashimoto encephalopathy – is it underdiagnosed in pediatric patients?
Neuropediatrics. 2002 Apr;33(2):86-9. PubMed PMID: 12075489.

38: Reinhardt MJ, Joe A, von Mallek D, Zimmerlin M, Manka-Waluch A, Palmedo H,
Krause TM. Dose selection for radioiodine therapy of borderline hyperthyroid
patients with multifocal and disseminated autonomy on the basis of
99mTc-pertechnetate thyroid uptake. Eur J Nucl Med Mol Imaging. 2002
Apr;29(4):480-5. Epub 2002 Jan 29. PubMed PMID: 11914885.
39: Vauth R, Joe A, Seitz M, Dreher-Rudolph M, Olbrich H, Stieglitz RD.
[Differentiated short- and long-term effects of a „Training of Emotional
Intelligence“ and of the „Integrated Psychologic Therapy Program“ for
schizophrenic patients?]. Fortschr Neurol Psychiatr. 2001 Nov;69(11):518-25.
German. PubMed PMID: 11704899.

40: Joe A, Hoegerle S, Moser E. Cervical lymph node sarcoidosis as a pitfall in
F-18 FDG positron emission tomography. Clin Nucl Med. 2001 Jun;26(6):542-3.
PubMed PMID: 11353305.

 

 

 

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